Conservative therapy refers to those treatments that use medical or physical measures. Individual approaches show a promising effect in Peyronie’s disease.
How to treat Peyronie’s disease
Conservative treatment methods should be fully exploited before using more invasive ways of treatment. Especially during the acute stage of Peyronie’s disease, conservative treatment methods can lead to successful results.
Xiapex® injection treatment
Xiapex injection treatment revolutionised conservative treatments of Peyronie’s disease when it was approved in the USA in 2015. It contains the active substance collagenase Clostridium histolyticum (brand name: Xiapex®), and has been approved by the European Commission in 2016 as well.
Latest studies show that an improvement of penile curvature can be achieved through a treatment with Xiapex®. A regular and continuous usage of penis extender devices has proven to positively affect an existing penile curvature. A combination of both treatments has resulted in promising outcomes.
Unfortunately, the distribution of the collagenase of the bacterium Chlostridium histolyticum (Xiapex) has been discontinued worldwide by the pharmaceutical company at the end of 2019. Only in the United States of America the collagenase is still distributed.
Following treatment methods can be neglected
Dietary supplement and aminobenzoate potassium capsules (brand name: Potaba), taken orally, only show negligible benefits.
The effectiveness of other injection treatments has been studied too. Aiming to reduce penile curvature by breaking up the plaque, following substances had been used:
- Cortisone
- Verapamil
- Interferon alpha
Shock wave therapy has also been in use, with the intention to positively affect the development of penile curvature. However, it was only possible to decrease the intensity of pain. Extracorporeal shock wave therapy showed no effect on the degree of curvature. If conservative treatment methods do not bring the desired results, surgical treatment should be considered.
I prefer a conservative treatment method – how to proceed?
During a consultation, Dr. Kuehhas will be able to ascertain if conservative treatment is appropriate in your case.
Dr Franklin Kuehhas is a medical specialist in the field of urology and andrology. He received his specialization training at the University College London. He also underwent his training at the prestigious University Hospital in Heidelberg (Germany) and at the University Hospital of Vienna (Austria). Dr Kuehhas focuses on the treatment of congenital and acquired penile curvatures (Peyronie’s disease). His research activities have resulted in many publications and improvements of surgical techniques such as the STAGE technique for penile curvature treatment.